Imperacer®
The Immuno-PCR Platform

Immuno-PCR

Imperacer®, the award-winning Immuno-PCR (IPCR) based ligand-binding assay platform. Chimera’s proprietary ultra sensitive immunoassay technology that combines the exquisite of ELISA-based antibody specificity with the most sensitive detection system in molecular biology: real-time qPCR.
The exponential signal amplification dramatically improves sensitivity and enables sub pg/ml detection.

Imperacer® assays combine ultra sensitivity with excellent precision, higher than usual drug tolerance, and minimal matrix effects. It´s broad assay range typically reduces the number of required sample dilutions to one, with no hook effect within physiological relevant concentrations.

Our proprietary immunoassay platform Imperacer® combines the preeminent specificity of antibody-antigen binding with the extremely powerful signal amplification of DNA analytics, using our patented antibody-DNA conjugates.
A double-stranded DNA-tag allows for exponential signal amplification of immunoassay binding events by PCR. This exponential amplification results in ultra sensitive assays with very broad dynamic ranges and - in consequence - to very dilution tolerant assays.

Imperacer® allows modification of the most sensitive assay procedure toward an assay with the minimal sample volume requirement at the needed level of sensitivity by customized AnySource® sample dilution.
Sensitivity can be employed for immunoassay quantification from microliter (µl) volumes of neat sample, still maintaining the needed sensitivity requirement of the study in trials involving microsampling or rare matrix samples.

We support your study design with ultra sensitive sample testing, courtesy of exponential, PCR driven signal amplification. Developed by the pioneers of the Immuno-PCR, Chimera Biotec’s proprietary Imperacer® technology brings this concept to professional bioanalytical sample testing.

Take advantage of Chimera Biotec‘s more than 20 years of in-depth experience as a specialty CRO for immunoassays which go beyond the scope of what is usually considered feasible.

Benefit from the best in class in immunoassay sensitivity!

Imperacer® Assays

Qualified
Qualified assays were developed, optimized and validated for specific reagents and matrices.

Offered
Offered assays can be activated on request.
The assay setup is on us, your commitment starts with the validation, which we perform respective to your purpose and under the quality regime of your choice - from internal decision making to full industry support according to guidances. A small assay activation fee will be used as a credit for the following validation and bioanalysis.