FAQ - Sample Handling

Find answers to your questions about sample preparation and dilution, freezing conditions, sample matrices and more.

What kind of sample preparation is required for Imperacer®?

  • You can use the same sample preparation protocol as for your standard immunoassay. No special treatment of your sample is necessary.

Is it possible to detect antigens in any sample matrix?

  • Yes, even without further purification or accumulation steps. In combination with the AnySource® sample dilution technology, Imperacer® assays already showed their increased performance in e.g. serum, plasma, CSF, tissue homogenate, urine, faeces, saliva, plant/food extracts and cell lysate. Typically the dilution of the sample in an adapted AnySource® sample dilution buffer reduces the background and inter-individual differences and thereby enhances the sensitivity of the assay. This unique combination of ultra sensitivity (Imperacer®) and sample dilution technology (AnySource®) allows, to circumvent nearly all limitations in classical immunoassays e.g. matrix interference, low sample volume, high drug tolerance in ADA testing and more.

Is it possible to dilute biological samples for Imperacer®?

  • Sample dilution is not only possible, it is recommended! Sample dilution is a common strategy to increase the sensitivity, reduce background, reduce the needed sample volume and reduce inter-individual differences. The AnySource® sample dilution technology has been developed to support the high sample dilution ratios, possible exclusively with Imperacer®.

Could the same protocol be used for alternative matrices?

  • No, changing assay specification results in the need of a new assay optimization. However Imperacer® assays can be adapted for the use in different matrices.

Can the same protocol be used after switching to alternative antibodies?

  • No, changing assay specification results in the need for a new assay optimization.