Lab-on-a-chip by ZWR
PROTEOMICS
Protein Analysis in an Optical Microfluidic System
In collaboration with the UAS Gelsenkirchen, the University of Technology Dortmund and headed by the team of Dr. Müller-Chorus at Böhringer Ingelheim microParts, Germany, Chimera Biotec developed a trendsetting lab-on-a-chip application designed for fast handheld devices. The project, using Chimera Biotec’s DNA-directed immobilization (DDI) technology, is sponsored by the Zukunftswettbewerb Ruhrgebiet, Germany.
In the framework of the project PROTEOMICS a new key technology for the fast and reliable multiplex analysis of proteins should be established. For this several innovative technologies will be combined: (i) an optical microfluidic system, (ii) a flexible bio-functionalization based on the self-assembly power of DNA-directed immobilization of protein-DNA conjugates and (iii) a fast and reliable handheld detection system.
We here work on the design and production of DNA-protein conjugates and the establishment of DDI-based applications and their adaptation to microfluidic systems.



