Doping Test by WADA
High sensitive detection of genetic and pharmacological manipulations of the myostatin signal transduction pathway by Immuno PCR fingerprint analysis
Working with the team of Dr. Patrick Diel at the German Sports University, Cologne, Germany, Chimera Biotec developed an ultrasensitive test for the detection of myostatin doping. The project, using Chimera Biotec’s Imperacer® platform, is sponsored by the World Anti-Doping Agency (WADA) in Montreal, Canada.
According to several experts, doping consumers are seeking to misuse substances that influence the myostatin level. There are several ways for myostatin doping: First by using drugs, which influence the signal transduction of myostatins directly and second by influencing genes, which regulate the myostatin level (gene doping). The myostatin protein belongs to the family of growth hormones and has significant influence on the skeleton muscles. Researchers found that a blockade of signal transduction of myostatins causes an immense growth of muscles.
